A high-density genetic linkage map is of particular importance in the fine mapping for important economic traits and whole genome assembly in aquaculture species.The channel catfish (Ictalurus punctatus), a species native to North America, is one of the most important commercial freshwater fish in the world.Outside of the United States, China has b
Personalized Immunotherapy in Colorectal Cancers: Where Do We Stand?
Colorectal cancer (CRC) is the second leading cause of cancer death in the world.Immunotherapy using monoclonal antibodies, immune-checkpoint inhibitors, adoptive cell therapy, and cancer vaccines has raised great hopes for treating poor prognosis metastatic CRCs that are resistant to the conventional therapies.However, high inter-tumor and intra-t
Pulsed Electromagnetic Fields in the treatment of fresh scaphoid fractures. A multicenter, prospective, double blind, placebo controlled, randomized trial
Abstract Background The scaphoid bone is the most commonly fractured of the carpal bones.In the Netherlands 90% of all carpal fractures is a fracture of the scaphoid bone.The scaphoid has an essential role in functionality of the wrist, acting as a pivot.Complications in healing can result in poor functional outcome.The scaphoid fracture is a troub